Behavioural correlates of hippocampal ensembles

We are currently analysing a rich dataset of 2-photon calcium imaging data from the mouse CA1 hippocampus to understand how hippocampal ensembles (groups of co-active neurons) encode information about behaviour, and in particular about movement and sensory stimuli. Our optical approach applied to transgenic mice allows us to distinguish specific neuron types. We are also particularly interested in the role of inhibition in organising ensembles of excitatory pyramidal cell and signalling behavioural variables.