Mechanisms and societal impact of psychedelics

Mechanisms

Our research investigates how psychedelics influence neural excitability and neuroplasticity. Using a combination of slice electrophysiology, pharmacology, and behavioural tests in mice, we delve into their effects at the cellular and network levels.

To extend these studies to the human brain, we collaborate with the Faculty of Medical Sciences at Newcastle University and the Neurosurgery Department at the Royal Victoria Infirmary. This partnership allows us to obtain small, living brain tissue samples resected during neurosurgeries. These acute human brain slices enable us to record neural activity for several hours, providing invaluable insights into how psychedelics act in the human brain.

Additionally, we study how psychedelics influence learning and emotional behaviour in both animal models and human participants.

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Societal impact

In parallel, we examine the broader implications of psychedelic use and regulation on mental health and society.

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Currently, we are seeking participants for an online anonymous survey on how psychedelics use affects mental health. We are seeking both users and non-users. It only takes 10-20 minutes to complete: https://t.co/9i7vDM9coa Please take part and spread the word to anyone who might be interested.